체질량지수 23 kg/m2 이상 남녀에서 8 주간의 의학 영양 치료에 의한 저열량 식이 섭취가 체격지수 및 혈액학적 지표에 미치는 영향

The principal objective of this study was to assess the effects of low-calorie diets(LCD) for 8 weeks of medical nutrition therapy in individuals with BMI in excess of 23 kg/m2. 41 over-weight or obese individuals (male=14, female=27, age 28.6±8.9 yrs), none of whom were diagnosed with a medical disease, were administered MNT 4 times over the study period. Approximately 1,100～1,300 kcal/day were prescribed by a dietitian, via individualized counseling. Anthropometric parameters, daily nutrient intake, and blood levels of leptin, insulin, and lipid profiles were measured prior to and after the 8 weeks of the intervention period. We noted significant reductions in body weight, body mass index (BMI), fat mass (FM), visceral adipose tissue (VAT), abdominal skin-fold thickness, and waist circumference in both men and women. The mean body weight losses in men and women were 3.2±0.6 kg/8 weeks and 2.8±0.6 kg/8 weeks, respectively. However, the % of lean body mass (LBM) in men and women was shown to increase significantly (p<0.05). The daily intake of calorie, fat, protein, vitamin E, folate, and iron were significantly reduced during the LCD period. Blood levels of lipids and glucose were in normal range, and evidenced no changes after LCD. However, the serum levels of leptin in female subjects were significantly reduced (p<0.001) from 8.9±4.8 ng/mL to 6.9±4.8 ng/mL. In conclusion, 8 weeks of LCD with individualized counseling by a dietitian effectively reduced body fat and visceral fat in both men and women with BMI in excess of 23 kg/m2.