Patent Foramen Ovale: Story Closed?
Patent Foramen Ovale: Story Closed?
Martin Köhrmann(Department of Neurology, Essen University Hospital, Essen, Germany); Peter D. Schellinger(Johannes Wesling Medical Center Minden, University Clinic RUB, Minden, Germany); Georgios Tsivgoulis(Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece); Thorsten Steiner(Department of Neurology, Frankfurt Hoechst Hospital, Frankfurt, Germany)
21권 1호, 23~30쪽
초록
The optimal treatment strategy for secondary prevention in patients with cryptogenic stroke and patent foramen ovale (PFO) has been a matter of controversy for decades. After three randomized trials failed to show a benefit of closure with an excess of complications in the interventional arm, two large recent trials suggest a benefit with regard of preventing further ischemic strokes. With this discrepancy in results it is important to discuss recent trials in detail and evolve an informed clinical approach for daily practice.
Abstract
The optimal treatment strategy for secondary prevention in patients with cryptogenic stroke and patent foramen ovale (PFO) has been a matter of controversy for decades. After three randomized trials failed to show a benefit of closure with an excess of complications in the interventional arm, two large recent trials suggest a benefit with regard of preventing further ischemic strokes. With this discrepancy in results it is important to discuss recent trials in detail and evolve an informed clinical approach for daily practice.
- 발행기관:
- 대한뇌졸중학회
- 분류:
- 신경과학