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학술논문Journal of Plant Biology(한국식물학회지)2020.04 발행KCI 피인용 1

m6 A mRNA Modifcation as a New Layer of Gene Regulation in Plants

m6 A mRNA Modifcation as a New Layer of Gene Regulation in Plants

Ji Woo Kim(서울대학교); Sangrea Shim(서울대학교); Hongwoo Lee(서울대학교); 서필준(서울대학교)

63권 2호, 97~106쪽

초록

N6 -methyladenosine (m6 A) is the most prevalent mRNA modifcation in higher eukaryotes. Technical advances in m6 A detec tion and mapping have allowed a comprehensive understanding of transcriptome-wide distribution of the RNA modifcation and its biological impacts especially in model plant systems. The m6 A modifcation is reversibly catalyzed by antagonistic actions of m6 A writers and erasers and the mRNA modifcation is biologically interpreted by m6 A readers. In this review, we summarized the recent understanding of molecular mechanisms underlying m6 A deposition and m6 A-regulated biological functions in diverse aspects of plant development. We also illustrated the evolutionary history of m6 A modifcation compo nents and discussed future perspectives of mRNA modifcation in plants.

Abstract

N6 -methyladenosine (m6 A) is the most prevalent mRNA modifcation in higher eukaryotes. Technical advances in m6 A detec tion and mapping have allowed a comprehensive understanding of transcriptome-wide distribution of the RNA modifcation and its biological impacts especially in model plant systems. The m6 A modifcation is reversibly catalyzed by antagonistic actions of m6 A writers and erasers and the mRNA modifcation is biologically interpreted by m6 A readers. In this review, we summarized the recent understanding of molecular mechanisms underlying m6 A deposition and m6 A-regulated biological functions in diverse aspects of plant development. We also illustrated the evolutionary history of m6 A modifcation compo nents and discussed future perspectives of mRNA modifcation in plants.

발행기관:
한국식물학회
분류:
생물학

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m6 A mRNA Modifcation as a New Layer of Gene Regulation in Plants | Journal of Plant Biology(한국식물학회지) 2020 | AskLaw | 애스크로 AI