Hydrogen sulfide‐activatable fluorescence turn‐on azide‐containing naphthalimide derivative
Hydrogen sulfide‐activatable fluorescence turn‐on azide‐containing naphthalimide derivative
Song Yi Yoo(Department of Chemistry, Sookmyung Women’s University); Chulhun Kang(The School of East-West Medical Science, Kyung Hee University); 이민희(숙명여자대학교); Lavanya Gopala(The School of East-West Medical Science, Kyung Hee University)
43권 11호, 1231~1235쪽
초록
Hydrogen sulfide (H2S) acts as a crucial biological and environmentalcomponent in a variety of processes. Abnormal levels of H2S endogenouslygenerated in human body are associated with various diseases. Meanwhile,H2S gas leaked from various manufacturing environments has a fatal effectagainst the human body. For this reason, H2S has been considered as a potentialbiomarker for the diagnosis and treatment of various human diseases, and as atoxic gas that should be detected when leaked to the workplace for the safety ofworkers. In this study, we synthesized an azide-containing naphthalimide derivativethat can play as a fluorescence turn-on probe for H2S.
Abstract
Hydrogen sulfide (H2S) acts as a crucial biological and environmentalcomponent in a variety of processes. Abnormal levels of H2S endogenouslygenerated in human body are associated with various diseases. Meanwhile,H2S gas leaked from various manufacturing environments has a fatal effectagainst the human body. For this reason, H2S has been considered as a potentialbiomarker for the diagnosis and treatment of various human diseases, and as atoxic gas that should be detected when leaked to the workplace for the safety ofworkers. In this study, we synthesized an azide-containing naphthalimide derivativethat can play as a fluorescence turn-on probe for H2S.
- 발행기관:
- 대한화학회
- 분류:
- 화학